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Provides expert engineering support and consultation to transform your imagination and ideas into functional 3D models with the use of additive manufacturing and laser cutting. Printing technologies include FFF and SLA with a wide variety of polymers including flexible, rigid, and high strength.

Providing large quantities of high-quality recombinant adeno-associated virus for gene therapy research. The technology and processes are developed to be “GMP transferable” to facilitate the transition from bench to bedside.

The lab offers training, testing, and standards development in the areas of additive fabrication, cold spray, and others. Available equipment includes Instron 3367, Danatronics Echo 9 galvanic corrosion tester, salt spray corrosion tester, Identron impact tester, Fischer poroscope, Falex wear tester, Zeiss Axioscope.

Cutting-edge 3D printing in metals and polymers for fabrication, research, training, and education. Printing technologies include DMLS, DED, SLS, FFF and PolyJet.

Rapid prototyping in a variety of materials with several types of 3D printing and CNC milling machines. Major equipment includes GCC LaserPro Spirit LS; Objet30; Roland MDX-540SA; Markforged Mark 2; and Roland MDX-40A; and Formlabs Form 2.

Includes a Philip’s Ingenia CX dStream 3.0T system, and RF coil labs supporting MRI imaging for humans and large or small animals.

Offers a wide-variety of analytical chemistry services, instruments, and technical expertise including GPC, HPLC, LC/MS, Surface Plasmon Resonance (SPR). The ACL provides quantitative and qualitative analysis, purity testing, and method development.

Designed to assist members of the research community on UMass and other five college campuses to conduct research using live animal imaging technologies. Equipment is capable of fluorescence and luminescence imaging independent of or concurrent with CT imaging.

The Small Animal Imaging lab (SAI) provides live, small animal imaging services utilizing a Bruker MRI, Mediso PET/CT and SPECT/CT, and IVIS Spectrum.

Provides transgenic, gene targeting, and mouse surgery service and training, performs microinjections of DNA into fertilized embryos to generate transgenic mice. Uses cutting-edge technologies, CRISPR/Cas9 genome editing, to generate gene knock-out or knock-in mice or other animal models.

Houses mice, rats, axolotl and zebrafish; purchases animals; trains researchers regarding proper animal care and use; monitors the safety of all personnel with laboratory animal contact; and provides technical and veterinary services and mouse breeding management. Includes a Barrier Suite and Perkin Elmer IVIS Lumina XRMS Series III.

Provides analytical and high resolution scanning probed based microscopy. This includes Atomic Force Microscopy (AFM) related techniques such as tapping mode, contact mode or conductive AFM as well as force measurements.

Facility evaluates, selects, and implements when needed the best of breed computational solutions for the analysis of biological data. This allows those who generate the data to be able to analyze it using state-of-the-art methods by reducing the computational expertise required to apply these methods.

Interactions between biological macromolecules like proteins, nucleic acids, lipids and their complexes, and small molecule interactions with these macromolecules.

Equipment for expression, separation, and isolation of biomolecules allowing users to culture cells including bacterial, yeast, insect, plant, and mammalian cells, and then separate biomolecules of interest ie. proteins, nucleic acids, natural products, and metabolites.

Bone imaging services, bone histology and histomorphometry services utilizing a microCT35 Scanco camera.

Spectral assessment of a wide variety of biological materials ranging from tissues to complex mixtures in the very far IR, near IR, visible and UV spectral ranges featuring a SENTERRA II confocal raman microscope.

Two cell culture facilities for both biological and bioengineering approaches. Biosafety cabinets, incubators and general wet lab supplies.

Exercise Intervention and Outcomes

• Diagnostic testing capabilities include exercise performance, VO2 max, exercise stress testing, strength testing, body composition (including abdominal obesity) and bone density evaluation.

Human Motion

• Assessment of human movement (free-living and robot-assisted) and human and robotic testing of sensor technologies.

Living Science

• Evaluate biosensor performance in healthy participants or participants who are at risk for chronic disease while living in a natural environment.

Room Calorimeter

• Capability to measure 24-hour human energy expenditure for purposes of movement sensor calibration and validation, and to conduct studies requiring assessment of energy balance and energy metabolism.

Sleep Monitoring

• Lab Equipped with partial and whole-head EEG systems for recording sleep physiology (sleep staging). A central control room will allow for on-line observation of sleep and monitoring of sleep in populations from infants to the elderly.

Offers massively parallel sequencing with the HiSeq 2500 and MiSeq platforms, next-generation sequencing library preparation from RNA and DNA, single-cell sequencing on the 10X Chromium platform; and nucleic acid quality assessments using Bioanalyzer, Tapestation, Nanodrop and Qubit assays. Additional instruments include a Nanostring nCounter Analysis System, and a QuantStudio 12K Flex Real-Time PCR.

A full-scale academic survey research center that conducts basic and applied research contributing to knowledge and understanding of important social issues. CSR maintains a professional interviewing staff, computer-assisted telephone facilities and survey sampling capacity, as well as the ability to conduct mail- and web-based surveys.

CRC is dedicated to efficient, reliable and high-quality study support for UMass clinical investigators to utilize the services as needed such as exams rooms for study visits, laboratory equipment and experienced staff to assist with clinical trial and research support services. Also offered is assistance with budget, contracts and regulatory expertise to support the management and conduct of clinical research.

Provides consultative and collaborative service in computational and molecular modeling.

Conquering Diseases is an easy-to-use web-based search tool to find, share and save clinical studies relevant to patients. It also provides educational resources to help patients and families learn about and find clinical studies.

Provides instrumentation for the determination of crystal structures using X-Ray diffraction techniques.

Provides services such as compliant access to data, data innovation research, and spearheading data collaborations.